It is necessary to consider that at various pathological conditions allocation of medicines through kidneys sometimes is essentially broken that can lead to considerable changes of shipping of pharmacological preparations, causing serious by-effects up to poisonings. Transformation of fibers, fats, carbohydrates, mineral substances and water occurs in close interaction with each other. In a metabolism of each of them there are features, and their physiological value variously, therefore the exchange of each of these substances can be considered separately. The adaptation of animals and the person to changing living conditions in environment is provided with activity of nervous system and realised through reflex activity. In the course of evolution have arisen наследственно the fixed reactions (unconditioned reflexes) which unite and co-ordinate functions of various bodies, carry out organism adaptation. The person and the higher animals in the course of individual life has qualitatively new reflex reactions which I. P.Pavlov named conditioned reflexes, including their the perfect form of the adaptation. While rather simple forms of nervous activity define reflex regulation of a homeostasis and vegetative functions of an organism, the higher nervous activity (ВНД) provides difficult individual forms of behaviour in changing living conditions. ВНД it is realised at the expense of dominating influence of a bark on all underlaying structures of the central nervous system. The basic processes dynamically replacing each other in ЦНС, excitation and braking processes are. Depending on their parity, force and localisation operating influences of a bark are under construction. Functional unit ВНД is the conditioned reflex. colchicine tablets